Andropause (also known as the male menopause) is the gradual decline in testosterone levels in middle-aged men. These declining testosterone levels have numerous signs and symptoms, and may include among others the following: Weakness, Fatigue, Disturbed sleep, Reduced libido, Osteoporosis, Heart disease, Irritability, Erectile dysfunction, Depression, anxiety, Reduced muscle mass, Reduced cognitive function. Take our A.D.A.M Questionnaire to see if you are suffering from low testosterone.